Collaborative Research Ventures

DIVISION OF BIOCHEMISTRY AND MOLECULAR BIOLOGY

Dr MG Casarotto

Structural Studies into the Mechanism of Dihydrofolate Reductase

Prof G Roberts
Centre for Mechanisms of Human Toxicity, University of Leicester, UK

Dr J Basran
Department of Biochemistry, University of Leicester, UK

Chitinase and Chitin binding proteins

Dr C Vorgias
Biology Department, Athens University, Greece

Prof H Schrempf
Universitat Osnabruk, FB Biologie/Chemie, Osnabruk, Germany

Dr M Richter
Department of Biochemistry, University of Kansas, USA

Prof J Andrews
RSBS, ANU

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Professor G Cox

Structure of Fo-F1-ATPase subunits by X-ray crystallography

Dr M Guss University of Sydney, NSW

ATP-binding cassette membrane transporters

Dr AJ Howells
Biochemistry & Molecular Biology, The Faculties, ANU

Prof RK Poole
Department of Microbiology, Kings College, London, UK

ATP-synthase mechanism

Prof AE Senior
School of Medicine & Dentistry, University of Rochester, New York, USA

Proton-energised membrane transporters

Prof AJ Pittard
University of Melbourne, VIC

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Professor Angela Dulhunty

Oxidation of ryanodine receptor from malignant hyperthermia pig muscle

Prof R Fink
University of Heidelberg, Heidelberg, Germany

Structure of DHPR binding domain on ryanodine receptor calcium release channel

Dr D McClennan
Banting & Best Research Institute, Toronto, Canada

Ultrastructural location of triadin in dyspedic mouse muscle

Dr P Allan,
Harvard Medical School, Boston, USA

Effect of pH on skeletal muscle ryanodine receptor

Dr G D Lamb
La Trobe University, VIC

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Dr P Foster

Characterisation of the role of eotaxin in the mechanism of pulmonary eosinophilic inflammation

Dr M Rothenberg
Childrens Hospital Medical Centre, University of Cincinnati, USA

The role of triadin in the regulation of Ca2+ release from the sarcoplasmic reticulum

Dr P Allen
Brigham & Women's Hospital, Harvard Medical School, Boston, USA

Modeling Chronic Inflammation in mice

Assoc Prof R Kummar
Department of Pathology, University of NSW, NSW

Role of parasitic infection in the predisposition to or protection against allergy

Drs K Ovington and L Milburn
Division of Biochemistry and Molecular Biology, The Faculties, ANU

Role of a novel marker for TH-2 cells in allergy

Dr T Coyle
Millenium Pharmaceutics Inc., Boston, USA

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Professor P Gage

Effects of conotoxins on sodium currents

Prof D Adams
Department of Physiology and Pharmacology, University of Queensland, QLD

Structure of the GABAA receptor

Dr M Parker
St Vincents Hospital, Darlinghurst, NSW

Analysis of subconductance states in ligand-gated receptors

Dr Shin-Ho Chung,
Dept of Chemistry, ANU

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Dr PL Cummins and Dr JE Gready

Development of QM/MM methodology for biomolecular QM/MM calculations

Dr A Rendell
ANU Supercomputer Facility

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Dr JE Gready

The agonist and antagonist sties of GABAC receptors

Dr M Chebib and Dr R Vandenberg
Department of Pharmacology, University of Sydney, NSW

Modelling cyclic peptides and metal-ion complexation

Dr M Ngu-Schwemlein
Department of Chemistry, Southern University A&M College, Baton Rouge, USA

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Dr JE Gready and Dr SP Greatbanks

Development of program interfaces for biomolecular QM/MM calculations

Dr A Rendell
ANU Supercomputer Facility

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Dr JE Gready and Mr SJ Titmuss

Development, evaluation and application of the linear-scaling QM method MOZYME for biomolecular calculations

Dr A Rendell and Dr A Bliznyuk
ANU Supercomputer Facility

Dr R Nobes
Fujitsu European Centre for Information Technology, London, UK

Dr J Stewart
Stewart Computational Chemistry, Colorado Springs, USA

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Dr PJ Harvey and Dr JE Gready

Use of NMR to study liver dysfunction in cirrhosis

Prof AJ McLean and Dr D Le Couteur
Canberra Clinical School, University of Sydney, NSW

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Dr R Hornig, Dr JE Gready and Prof IG Young

Electron microscopy studies of interleukin-5 receptor

Dr S Stowe
Electron Microscopy Unit, RSBS, ANU

Dr P Carr
Protein Crystallography Group, RSC, ANU

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Dr WA King and Dr JE Gready

Computational studies of the mechanism of the photosynthetic enzyme, Rubisco

Prof TJ Andrews
Molecular Plant Physiology Group, RSBS, ANU

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Dr DA Jans

Nuclear localisation of the interferon induced IF16 protein

Dr J Trapani/Dr R Johnson
Austin Research Institute, Heidelberg, VIC

The ERN signalling pathway

Prof M-J Gething
Department of Biochemistry, University of Melbourne, VIC

Nuclear and nucleolar localisation of granzyme B

Dr J Trapani / Dr V Sutton
Austin Research Institute, Heidelberg, VIC

Receptor- and Signal-Mediated Targeting of Plasmid-DNA and Photosensitiser Molecules to the Nucleus of Specific Cell Types with Application in Gene Therapy and Cancer Phototherapy

Prof A Sobolev,
Research Center For Molecular Diagnostics & Therapy, Moscow

A regulated nuclear localisation signal in MAP2

Dr K Loveland
Monash Medical Centre, Melbourne, VIC

Nuclear targeting by PTHrP

Dr M Lam / Dr M Gillespie
St Vincent's Institute for Medical Research, Fitzroy, VIC

Regulation of nuclear localisation of the Dengue Virus NS5 protein

Dr S Vasudevan
James Cook University of North Queensland, QLD
(IAS Australian Universities' Research Collaborative Scheme)

Kinetics and Mechanism of Viral Protein Transport To The Nucleolus

Prof R Lixin
Anhui Medical University, Hefei Anhui China, DIST (Dept. of Industry, Science & Technology) Bilateral Science & Technology Program, 1997/8

Dual nuclear localisation signals of SRY

Dr V Harley
Howard Florey Institute, Parkville, VIC

Nuclear targeting pathways for IGFBPs

Dr L Schedlich
Kolling Medical Research Institute, Sydney, NSW

Evolutionary aspects of NLS-binding protein subunits and their regulation of nuclear protein import

Prof N Raikhel
Michigan State University, East Lansing, USA

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Dr P Jeffrey

Study of the effect of temperature on the aggregation state of antifreeze protein

Dr R Solomon
CSIRO, Canberra

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Dr KI Matthaei and Prof IG Young

The role of IL-5 in tumour progression

Dr V Apostolopolous and Prof I McKenzie
Austin research Institute, Heidelberg, VIC

The role of IL-5 in reproduction

Dr S Robertson
Department of Obstetrics, The University of Adelaide, SA

The role of IL-5 in smooth muscle hyperreactivity of the gut

Mr B Vallence and Prof S Collins
Division of Gastroenterology, McMaster University,
Department of Medicine, Hamilton, Ontario, Canada

The role of IL-5 in mucosal immunity

Dr B Bao and Prof A Husband
Veterinary Pathology, University of Sydney, NSW

The role of IL-5 and eosinophils in tumour rejection

Dr M Rothenberg
Childrens Hospital Medical Centre, University of Cincinnati, USA

The role of IL-5 in eosinophil precursor differentiation

Prof J Denburg
Department of Medicine, McMaster University,
Hamilton, Ontario, Canada.

The role of the mouse homologue of "flightless" in vivo

Dr H Campbell
Molecular Evolution and Systematics, RSBS, ANU

Neuronal development in IL-5 deficient mice

Dr R Egan
Senior Director, Allergy Division, Shering-Plough Research Institute, Kenilworth, NJ, USA

Behavioral studies in IL-5 deficient mice

Dr J Homewood
Psychology Department, Macquarie University, Sydney, NSW

Hookworm infection in IL-5 deficient mice

Prof P Prociv
Department of Parasitology, The University of Qld, QLD

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Dr M F Shannon

Mechanisms of HMGI(Y) activation of T cell cytokine genes

Dr R Reeves
Department of Biochemistry and Biophysics, Washington State University, Pullman, USA

Function of the coactivator PC4 in HIV gene transcription (With Dr A Holloway)

Dr M Meisterernst
Laboratory of Molecular Biology-Genzentrum, Ludwig-Maximilians-University, Munich, Germany

Dr D Harrich
HIV Research Laboratory, Sir Albert Sakzewski Virus Research Centre, Royal Childrens Hospital, Herston QLD

The role of Cold Shock Domain proteins in cytokine gene transcription

Dr L Coles
Division of Human Immunology, Hanson Centre for Cancer Research, Adelaide, SA

Transgenic Models of cytokine gene transcription

Dr P Cockerill
Division of Human Immunology, Hanson Centre for Cancer Research, Adelaide, SA

The role of c-Rel and C/EBP in ICAM1 gene transcription

Dr K Catron
Boehringer Ingelheim Pharmaceuticals, Ridgefield, Conn., USA

Development of the GM-CSF E21R antagonist

Dr A Lopez and Prof M Vadas
Division of Human Immunology, Hanson Centre for Cancer Research, Adelaide, SA

__________________

Dr D Shaw

Structure / function of milk proteins

Dr K Bel
Department of Physiology, University of Queensland, QLD

Lactation physiology

Dr KR Nicholas
Victorian Institute of Animal Science, Melbourne, VIC

Human lens proteins

Prof RJW Truscott
Australian Cataract Research Foundation, University of Wollongong, NSW

Toxins

Prof GF King
Department of Biochemistry, University of Sydney, NSW

__________________

Dr D Tremethick

Phosphorylation on nucleosome spacing by HMGs 14 and 17

Dr M Bustin
NIH, Bethesda, MD, USA

Stimulation of transcription from different RNA polymerase II promoters by high mobility group proteins 1 and 2.

PL Molloy
CSIRO, Division of Biomolecular Engineering, Laboratory for Molecular Biology, North Ryde, NSW

The transcription complex of the 5S RNA gene, but not TFIIIA alone, prevents nucleosomal repression of transcription.

K Zucker, A Worcel
Department of Biology, University of Rochester, New York, USA

Partial purification, from Xenopus laevis ocytes, of an ATP-dependent Activity Required for Nucleosome Spacing in Vitro.

M Frommer
Kanematsu Laboratories, Royal Prince Alfred Hospital, Camperdown, NSW

HMGs 14 and 17 can Space Nucleosomes in Vitro.

H Drew
CSIRO, Division of Biomolecular Engineering, Laboratory for Molecular Biology, North Ryde, NSW

The mechanism by which a transcription complex forms on the mouse dihydrofolate reductase promoter when the promoter is assembled in chromatin

Dr P Farnham
McArdle Laboratory for Cancer Research, University of Wisconsin, USA

__________________

Professor IG Young

Human low molecular weight B cell growth factor.

Dr EM Benson
Department of Medicine, Westmead Hospital, NSW

__________________________________________________________________________________________

DIVISION OF IMMUNOLOGY AND CELL BIOLOGY

Dr J Banyer

Genetic differences between subsets of human NK cells

Dr H Warren,
Canberra Hospital, ACT

__________________

Professor RV Blanden, Drs. H Rothenfluh & C Bruce

Mechanisms of somatic variation of V genes

Dr EJ Steele,
University of Wollongong, NSW

Evolutionary origin of germline V genes in the immune system

Dr EJ Steele,
University of Wollongong, NSW

Dr G Weiller,
Research School of Biological Sciences, ANU

__________________

Dr IA Clark

The role of nitric oxide in the pathogenesis of falciparum malaria

Dr M Molyneux
Wellcome Trust Centre, Blantyre, Malawi

Dr T Taylor
Dept. of Internal Medicine, Michigan State University, USA

Dr R Carr
St Thomas's Hospital, London, UK

Dr K Rockett
Dept of Paediatrics, University of Oxford, John Radcliffe Hospital, Oxford, UK

__________________

Dr P Cooper

Adjuvant activity of gamma inulin

Dr P Goldwater,
Adelaide Children's Hospital, SA

Prof I Frazer and Dr R Tindle,
Princess Alexandra Hospital, Brisbane, QLD

Dr R Gupta,
Massachusetts Public Health, Biological Laboratories, Boston, USA

Dr F Vogel,
AIDS Vaccine Research Branch, NIH, Bethesda, USA

Dr P Fuentes,
Universitat Autonoma de Barcelona, Spain

Dr G Guillen,
Centre for Genetic Engineering & Biotechnology, Havana, Cuba

Dr DO Willenborg,
Neurosciences Research Unit, Canberra Hospital, ACT

Dr I Pinchasi,
TEVA Pharmaceutical Industries, Israel.

Dr N Garon,
Smithkline Beecham, Rivensart, Belgium

Dr J Adair,
Axis Genetics Plc, Cambridge, UK

Prof G Tannock
Royal Melbourne Institute of Technology, VIC

__________________

Dr WB Cowden

The role of nitric oxide in autoimmune disease

Dr K Rockett,
Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK

The role free radicals in vascular disease

Dr R Stocker,
The Heart Research Institute, Sydney NSW

__________________

Dr AJ Hapel

Analysis of the role of interleukin-3 and CSF-1 in synergistic signalling by targetting of their receptor genes

Prof ER Stanley,
Albert Einstein College of Medicine, New York, USA

Targetted dissruption of the c-fms gene

Prof ER Stanley,
Albert Einstein College of Medicine, New York, USA

Mechanism of cell death in Ross-River virus-infected striated muscle

Dr B Lidbury,
University of Canberra, ACT

__________________

Drs AJ Hapel and J Banyer

Differentiation of myb-transformed haematopoietic progenitor cells

Assoc Prof T Gonda,
Hanson Centre for Cancer Research, Adelaide, SA

Isolation of Ross-River virus resistance genes from macrophage "RAW" cells

Dr B Lidbury,
University of Canberra, ACT

__________________

Dr M Hulett

Cloning and characterisation of a novel family of tetraspan molecules

Dr M Cancilla
The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC

Dr T Luft
Ludwig Institute for Cancer Research, Melbourne, VIC

Dr K Loveland
Institute of Reproduction and Development, Melbourne, VIC

Dr M Hogarth
Austin Research Institute, Melbourne, VIC

Dr P Darey and Dr M Smyth
Austin Research Institute, Melbourne, VIC

Dr S Russell
Austin Research Institute, Melbourne, VIC

Dr L Baker and Prof G Sutherland
Women's and Children's Hospital, Adelaide, SA

Structure and function of Fc Receptors

Dr M Hogarth and Dr B Wines
Austin Research Institute, Melbourne, VIC

__________________

Dr G Karupiah

C-X-C chemokines and immunity to viral infections

Dr J Farber,

National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA

Nitric oxide in antiviral defense and immunopathology

Prof C Nathan & Dr J MacMicking,
Division of Haematology-Oncology, Department of Medicine, Cornell University Medical College, New York, USA

Genetic control of early immune responses to pox and herpes viruses

Dr A Scalzo,

Department of Microbiology, University of Western Australia, Perth, WA

Immunocytochemistry for detection of cytokine and antibody producing cells during viral infection

Dr E Claassen,
DLO-Institute for Animal Science & Health, Edelhertweg, AB Lelystad, The Netherlands

Induction of effector mechanisms in the lung following intestinal immunisation

Ms R Foxwell and Prof A Cripps,
Faculty of Applied Science, University of Canberra, ACT

C-C chemokines and the immune response to viral infections

Prof B Sherry,
Picower Institute, New York, USA

Response of mice lacking the CC chemokine receptor 1 to viral infections

Dr P Murphy,
Laboratory of Host Defense, National Institute of Allergy and Infectious Diseases, National Institute of Health, Bethesda, Maryland, USA

__________________

Dr M Lobigs

Protective immune responses in mice vaccinated with recombinant vectors expressing flavivirus genes

Drs RA Hall and IS Mackenzie,
Department of Microbiology, University of Queensland, Brisbane, Qld

__________________

Drs M Lobigs & A Müllbacher

Allele-dependent selectivity in peptide translocation by Syrian hamster TAP, in vitro

Drs. F Momburg and GJ Hämmerling,
Molecular Immunology, German Cancer Research Center, Heidelberg, Germany

Effect of flavivirus infection on supply of peptides for association with MHC class I

Dr F Momburg,
Molecular Immunology, German Cancer Research Center, Heidelberg, Germany

__________________

Dr A Müllbacher

Oral induced T cell tolerance

Dr J Chin,
Elizabeth MacArthur AG Institute, NSW Department of Agriculture, Camden, NSW

__________________

Dr A Müllbacher & Prof RV Blanden

Role of TNF and lymphotoxin in viral infection

Dr J Sedwick ,
DNAX Research Institute, Palo Alto, CA, USA

Dr Heiner Körner,
Centenary Institute, Sydney, NSW

Adenovirus mediated liver pathology

Dr H Hayder,
Canberra, ACT

__________________

Drs A Müllbacher & M Lobigs

The role of T cell serine proteases in cell cytotoxicity and viral pathogenesis

Dr M Simon,
Max Planck Institute für Immunbiologie, Freiburg, Germany

Allorecognition

Dr R Langman,
Conceptual Immunology, The Salk Institute, La Jolla, CA, USA

__________________

Drs A Müllbacher, M Lobigs & Prof RV Blanden

The role of MHC-class I in antigen presentation

Dr Jon Yewdell,
Viral Immunology Laboratory, National Institute of Allergy and Infection Diseases, National Institutes of Health, Bethesda, USA

__________________

Drs A Müllbacher & M Simon

The role of granzyme A in fungal infection

Dr R Ashman,
Oral Biology and Pathology, University of Queensland, Brisbane, QLD

The role of granzymes and perforin in cytomegalovirus infections

Dr S Landolfo,
Department of Public Health, Medical School, Turin, Italy

The role of granzymes in herpes virus infection

Drs. R Pereira and A Simmons,
Herpes Research, Infectious Diseases Laboratories, Institute of Medical & Veterinary Science, Adelaide, SA

__________________

Drs A Müllbacher, M Simon & P Waring

The role of poxvirus encoded serpins in cytotoxic T cell induced apoptosis

Dr R Wallich,
Department of Immunology, University of Heidelberg, Heidelberg, Germany

__________________

Drs A Müllbacher & P Waring

The role of granzymes in the induction of apoptosis

Dr M Simon,
Max Planck Institute für Immunbiologie, Freiburg, Germany

__________________

Professor C Parish

Sulfated oligosaccharides as anti-viral agents

Dr A Cunningham,
Westmead Hospital, Sydney, NSW

Inhibition of uveitis by oligosaccharides

Dr K Williams,
Flinders Medical Centre, Bedford Park, SA

Carbohydrate-based anti-metastatic compounds

Dr R Anderson,
Peter MacCallum Cancer Institute, Melbourne, VIC

Prof D Morris,
Department of Surgery, The St George Hospital, Kogarah, NSW

Drs H Wheeler and N Pavlakis
Royal North Shore Hospital, Sydney, NSW

Analysis of cell adhesion molecules on human lymphocytes

Dr H Warren,
Canberra Hospital, ACT

Novel multimeric technology for cell surface molecules

Dr B Cornell,
AMBRI, Sydney, NSW

Histidine-rich glycoprotein deficiencies and autoimmune disease

Prof P Gatenby,
Canberra Hospital, ACT

__________________

Dr A Ramsay

Antiviral and mucosal immunity in cytokine gene knockout mice

Dr M Kopf,
Basel Institute for Immunology, Switzerland

Replication-defective Salmonella vectors as carriers for oral DNA vaccines

Dr R Strugnell,
University of Melbourne, VIC

Cytokines and dendritic cells in oral tolerance and mucosal immune responses, and non-replicating oral vaccines for immunocontraception

Dr KW Beagley,
University of Newcastle, NSW

Immunobiology of murine cytomegalovirus and its potential as a vaccine vector

Dr M Lawson and Prof G Shellam,
University of Western Australia, Perth, WA

Recombinant poxvirus-based immuno-contraceptive vaccine development

Dr R Jackson,
CSIRO, Gungahlin, ACT

Genetic vaccine strategies for mucosal immunity against HIV

Dr S Kent
MacFarlane Burnet Centre, Melbourne, VIC

__________________

Professor IA Ramshaw

Design of viruses for the biological control of vertebrate populations

Drs P Jackson, PKerr,
Division of Wildlife and Ecology, CSIRO, Canberra, ACT

Investigation into immunogenicity of DNA vaccines

Prof H Robinson,
Department of Pathology, University of Massachusetts, Worcester, MA USA

The use of vaccinia virus expressing IL-2 in the treatment of lung cancer

Prof B Robinson,
Sir Charles Gardner Hospital, Nedlands, WA

HIV polytope vaccines

Dr A Suhrbier,
QIMR, Brisbane, QLD

Dr R Ffench,
Westmead Hospital, NSW

__________________

Dr H Rothenfluh

Molecular analysis of a persistent mutant of virulent Ross River Virus

Dr B Lidbury,
University of Canberra, ACT

__________________

Dr S Thomson

Polyepitope vaccine for Papilloma virus infection and cervical cancer

Assoc Prof B Tindle,
Sir Albert Sakzewski Virus Research Centre, Brisbane QLD

Polyepitopes to treat Burkitt's lymphoma and glandular fever

Prof D Moss, Drs R Khanna and M Sherritt,
Queensland Institute of Medical Research, Brisbane, QLD

__________________

Drs S Thomson, W Cowden & Prof IA Ramshaw

Delivery of multiple EAE epitopes

Dr D O Willenborg,
Neurosciences Research Unit, Canberra Hospital, ACT

__________________

Drs S Thomson & G Karupiah

Recombinant ectromelia viruses expressing immune modulating antigens

Dr N Davis-Poynter,
Department of Microbiology, University of Western Australia, Nedlands, WA

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Dr P Waring

Structure activity studies of naturally occurring and synthetic members of the epipolythiodioxopiperazine class of immunomodulating fungal toxins

Dr C Chai
Chemistry, The Faculties, ANU

Studies into the increased expression of cell surface carbohydrate residues during apoptosis - their role in phagocytic recognition

Dr J Beaver,
Applied Science, University of Canberra, ACT

Apoptosis in muscle cells during exercise

Dr J Beaver,
Applied Science, University of Canberra, ACT

Cell cycle analysis as a tool for the determination of nutritional status in fish

Dr J Kalish,
BOZO, The Faculties, ANU

The measurement of oestrogenic activity of pollutants in local water supplies

Dr J Kalish,
BOZO, The Faculties, ANU

The biological activity and effects on mitochondrial function of gold phosphine complexes and their clinical potential as antiproliferative agents

Dr Geoff Salem,
Chemistry, The Faculties, ANU

__________________________________________________________________________________________

DIVISION OF MOLECULAR MEDICINE

Dr N G Ardlie

Influence of fatty acid content on the oxidisability of LDL in subjects with coronary artery disease

Dr D A McGill
Department of Cardiology, The Canberra Hospital, ACT

Low density lipoprotein oxidation in haemochromatosis

Dr M L Bassett
Department of Gastroenterology, The Canberra Hospital, ACT
&
Dr J E Dahlstrom and Dr S Jain
Department of Anatomical Pathology, The Canberra Hospital, ACT

__________________

Professor P Board

Molecular genetics and structure of the glutathione S-transferases

Prof B Mannervik
Biochemistry Department, Uppsala University, Sweden

Structural analysis of glutathione S-transferases

Dr M Parker
St Vincents Medical Research Institute, Melbourne, VIC

Regulation of mouse Theta class GST genes

Dr W Pearson
Department of Biochemistry, University of Virginia Health Sciences Center, Charlottesville, USA

Use of GST genes to create drug resistance in hematopoietic stem cells

Dr M Webb
Haematology, The Canberra Hospital, ACT

Mapping human genes

Dr G Webb
Genetics Department, Queen Elizabeth Hospital, Adelaide, SA

Parkinson's Disease, Pesticides and glutathione transferase polymorphisms

Dr D LeCouteur

Department of Pharmacology, University of Sydney and Canberra Clincal School, The Canberra Hospital

Function of the Zeta class GSTs

Dr MW Anders

Dept. of Pharmacology and Physiology, University of Rochester Medical

Chromosomal mapping of human genes

Dr G Sutherland and Mrs E Woolatt
Dept of Cytogenetics and Molecular Genetics, Women's and Children's Hospital, Adelaide, SA

__________________

Dr R Baker

Ubiquitin-specific proteases in cancer

Assoc Prof D A Gray
Ottawa Regional Cancer Centre, University of Ottawa, Ontario, Canada

Ubiquitin-specific proteases in eye development

Dr J Fischer-Vize
Department of Zoology, University of Texas, Austin, USA

Ubiquitin-ribosomal fusion proteins in yeast and mammals

Prof REH Wettenhall
Dept of Biochemistry, University of Melbourne, VIC

Mapping human and mouse genes

Dr G Webb
Genetics Department, Queen Elizabeth Hospital, Adelaide, SA

Chromosomal mapping of human genes

Dr G Sutherland and Mrs E Woolatt
Dept of Cytogenetics and Molecular Genetics, Women's and Children's Hospital, Adelaide, SA

__________________

Dr S Easteal

The genetic basis of common mental disorders Assocd with anxiety and depression

Prof AS Henderson and Dr A Jorm
Social Psychiatry Research Unit, ANU
&
Prof M Prior
Psychology Department, Melbourne University, VIC

Evolution of class I alcohol dehydrogenase genes in primates

Prof R Holmes and Dr I Beecham
Griffith University

Genetics and Evolution of human alpha actinin-3

Drs K N North and Nan Yang
Neurogenetics Research Unit, Royal Alexandra Hospital for Children, Sydney, NSW
&
Dr A H Beggs
Harvard Medical School, Boston, USA

The evolution of primate nuclear genomes

Dr S O’Brien & Dr Leslie Lyons
National Cancer Institute, Frederick, MD, USA

Development of methods for analysing the evolution of multigene families

Prof S Wilson
School of Mathematical Sciences, ANU

__________________

S Easteal, X Gao & G Chelvanayagam

Analysis of HLA sequence variation

Drs G Thomson & W Klitz
University of California, Berkeley, USA

__________________

Dr X Gao

Nucleotide sequence polymorphism of HLA class I genes in Aboriginal Australians : implications for Aboriginal health and transplantation

Prof J McClusky
Flinders Medical School, Adelaide, SA
&
Prof B Boettcher
Newcastle University, NSW
&
Dr A Veale
National Centre for Epidemiology and Population Health, ANU
&
Dr B Currie
Menzies School of Health Research, Darwin, NT

Diversity of HLA-B27 in Chinese patients with ankylosing spondylitis

Prof F H Kong
North Tai Ping Road Hospital, Chinese Academy of Medicine, China

__________________

Dr G Chelvanayagam

Peptide epitopes

Dr V Apostolopoulos & Prof IFC McKenzie
The Austin Research Institute, Heidelberg, VIC

Structure functions and mechanisms of GSTs

A Prof M Parker
St Vincent's Institute of Medical Research, Melbourne, VIC

Functional properties of HLA molecules

Dr X Gao
National Cancer Institute, Frederick MD, USA

__________________

Dr L Jermiin

Phylogenetic and comparative studies of the evolution of insect mitochondrial DNA

Ms M Chiotis, Mr W T Tay, Ms N Dobric & Prof R H Crozier
School of Genetics and Human Variation, La Trobe University, VIC

Phylogenetic and comparative studies of the evolution of bird mitochondrial DNA

Dr G Borgia
Department of Zoology, University of Maryland, USA
&
Dr L Christidis Department of Ornithology, Museum of Victoria, VIC
&
Prof R H Crozier, Dr R M Kusmierski & Dr M Westerman
School of Genetics and Human Variation, La Trobe University, VIC
&
Dr R Schodde
Division of Wildlife and Ecology, CSIRO, Canberra, ACT
&
Mr I A W Scott & Dr D D Shaw
Research School of Biological Sciences, ANU

__________________

Dr L S Jermiin and Dr S Easteal

Analysis of 16S rRNA and amylase genes from archaebacteria

Dr I R Beacham, Mr R A Jones & Dr B Patel
School of Biolmolecular and Biomedical Science, Griffith University, QLD

Development of new methods for assessment and phylogenetic analysis of nonstationary DNA sequence data

Prof R H Crozier
School of Genetics and Human Variation, La Trobe University, VIC
&
Prof E R Smith
School of Mathematics, LaTrobe University, VIC
&
Prof S R Wilson
Centre for Mathematics and Its Applications, ANU

Development of ultrafast maximum likelihood programs forDNA and protein sequence analysis on supercomputers

Dr M Kahn
The ANU Supercomputer Facility, ANU
&
Dr R Brown
The ANU Supercomputer Facility, ANU
&
Dr B D McKay
Department of Computer Science, ANU
&
Dr M J Wolf
Computer and Information Science Department, Mankato State University, USA

A comparative evolutionary study of metazoan mitochondrial DNA and protein

Prof R H Crozier
School of Genetics and Human Variation, La Trobe University, VIC
&
Prof D Graur
Department of Zoology, TelAviv University, Israel
&
Dr M D Pagel
Department of Zoology, University of Oxford, UK

Analysis of ancient human DNA

Dr A Thorne
Department of Prehistory and Anthropology, ANU
&
Drs J Peacock and E Dennis
CSIRO, Division of Plant Industry

__________________

Dr GA Huttley

Comparative evolutionary analysis of the HLA and other genomic regions

Dr G Thomson
Department of Integrative Biology, UC Berkley, USA

Assessing evolutionary concordance of case and control populations

Prof S R Wilson
School of Mathematical Sciences, ANU

A method for gene mapping in admixed populations

Dr G Nelson
Laboratory of Genomic Diversity, National Cancer Institute, Frederick, Maryland, USA

Genomic analysis of linkage disequilibrium

Drs S J O’Brien, M Carrington, and M W Smith
Laboratory of Genomic Diversity, National Cancer Institute, Frederick, Maryland, USA

Functional and evolutionary implications of genetic diversity at plant disease resistance loci

Drs J G Ellis, and P Dodds
Division of Plant Industry, CSIRO, Canberra

__________________

Dr G A Huttley and Dr S Easteal

Analysis of genetic diversity at cancer susceptibility genes in humans and other primates

Dr D J Venter
Peter MacCallum Cancer Institute, Melbourne, VIC
&
Dr J L Hopper
Centre for Genetic Epidemiology, University of Melbourne, VIC

A role for mutation at methylated nucleotides in male-biased molecular evolution

Prof S R Wilson
School of Mathematical Sciences, ANU
&
Dr I Jakobsen,
Institute for Molecular Evolution, Pennsylvania State University, USA

The effect of varying demographic and evolutionary regimes on patterns of linkage disequilibrium

Prof S R Wilson
School of Mathematical Sciences, ANU

__________________

Prof C Goodnow

Genetic analysis of B cell development and activation (supported by the Human Frontiers Science Program)

Dr M Thomas
Dept of Pathology, Washington University, St. Louis, MO, USA
&
Prof K Rajewsky
Institute for Genetics, University of Cologne, Germany

Role of Lyn kinase and interactions with SHP-1 phosphatase in B cells

Dr M Hibbs
&
Dr A Dunn
Ludwig Institute for Cancer Research, Melbourne VIC

Role of CD22 and interactions with SHP-1 phosphatase in B cells

Dr E Clark
University of Washington, Seattle, USA

Gene expression during B cell activation, anergy and immunosuppression

Dr R Glynne
Dept of Microbiology and Immunology, Stanford University, CA, USA
&
Dr D Mack
Affymetrix Inc, Santa Clara, CA, USA

Calcium regulation in B cell tolerance and activation

Dr R Dolmetsch
&
Dr R Lewis
Dept of Molecular and Cellular Physiology, Stanford University, CA, USA

Regulation of CD4 T cells and plasma cells

Dr J Healy
&
Prof M M Davis
Dept of Microbiology and Immunology, Stanford University, CA, USA

Effect of NOD genes on regulation of islet-reactive CD4 T cells

Dr L Wicker
Merck Research Labs, Rahway NJ, USA

Effects of dysregulated B7.2 expression on B-T interactions

Prof J Allison
&
Dr S Fournier
University of California, Berkeley, USA

__________________

Dr M Kohonen-Corish

Genetic susceptibility to human colorectal cancer

Dr J St John and Dr F Macrae
Royal Melbourne Hospital, Parkville, VIC
&
Dr J Wijnen and Dr P Meera Khan
Department of Human Genetics, University of Leiden, The Netherlands
&
Dr S Forrest
The Murdoch Institute, Melbourne, VIC
&
Dr E Edkins
Genetic Services of Western Australia, Princess Margaret Hospital for Children, Perth, WA
&
Dr J Kirk
Department of Medical Oncology, Westmead Hospital, Sydney, NSW
&
Prof J Jass
Queensland Institute for Medical Research, University of Queensland, Herston, QLD

Genetic analysis of the urokinase receptor gene in colorectal cancer

Dr G Chenevix-Trench, Dr J Young
Queensland Institute of Medical Research, The Bancroft Centre, Herston, QLD

Cancer colitis model in Msh2 deficient mice

Dr G Buffinton
St Bartholomew's and Royal London School of Medicine and Dentistry, London, UK
&
Dr H te Riele
The Netherlands Cancer Institute, Amsterdam
&
Dr J Dahlstrom
The Canberra Hospital, ACT

__________________

Professor K Lafferty

Islet Mass and Regeneration in the NOD Mouse

Prof S Bonner-Weir
Research Division, Joslin Diabetes Center, Boston, MA, USA

Chemokine involvment in the pathogenesis of autoimmune diabetes

N Solvason
Anergen Inc., USA

__________________

Dr P McCullagh

Development of the B lymphocyte system in the fetal lamb

Dr C Press and Prof T Landsverk
Royal Norwegian Veterinary School, Oslo, Norway

Maturation of the capacity of the gut-Assocd lymphoid tissue to respond to parasitc infection

Dr S McClure
CSIRO, Mcmaster Laboratory

Factors determining normal maturation of fetal pulmonary tissue

Dr M Peek
Department of Obstetrics and Gynaecology, Canberra Clinical School, University of Sydney

Modelling of lymphocyte migration using a frequency domain approach.

Dr M Durisova
Institute of Experimental Pharmacology, Slovak Academy of Sciences
&
Dr L Dedkik
Faculty of Mechanical Engineering, Slovak Technical University, Bratislava, Slovak Republic

__________________

Dr CJ Simeonovic and Clin. Assoc Prof JD Wilson

Neuroprogenitor cells for delivery of immunoregulatory cytokine genes to pig proislet xenografts in mice.

Dr R Taylor
Dept of Animal Science, University of Sydney, NSW

__________________________________________________________________________________________

DIVISION OF NEUROSCIENCE

Dr JM Bekkers

ATP-gated ion channels in the rat brain.

Dr F Edwards,
Department of Physiology, University College London, UK

Single-channel properties of the slow AHP current

Prof B Sakmann,
Max Planck Institute for Medical Research, Heidelberg, Germany

Oscillatory properties of hippocampal pyramidal cells

Dr O Paulsen,
Department of Pharmacology, University of Oxford, UK
Prof R Olsen,
Dept. of Physiology, UCLA, USA

__________________

Dr MC Bellingham

Dynamic clamp studies of ionic currents in brainstem neurones

Dr P Pilowsky
Dept Physiology and Neurological Surgery, University of Sydney, NSW

Cholinergic neuromodulation of respiratory rhythm generation

Dr G Funk
Dept Physiology, University of Auckland, NZ

__________________

Dr M Crouch

The role of PI 3-kinase in cytoskeletal regulation.

Dr P A Naccache,
University Laval, Quebec, Canada

The role of nuclear phospholipase C in regulation of cell proliferation

Prof R Irvine and Dr S McNulty,
University of Cambridge, UK

__________________

Dr CE Hill

Electrical properties of iridial arterioles of the rat

Drs GDS Hirst, FR Edwards,
Department of Zoology, University of Melbourne, VIC

Immunohistochemical localisation of alpha1B adrenergic receptors in rat iris.

Prof RD Graham, Dr S Chen,
Victor Chang Cardiac Research Institute, Darlinghurst, NSW and
Prof RD Brown,
The Edward Hines Jr, VA Hospital, Research Service (151), Hines, Illinois, USA

__________________

Dr IA Hendry

Neuromuscular growth factors

Dr I MacLennan,
Department of Anatomy, University of Otago, NZ

Effects of disruptions of synaptic formation on neurotrophin localization

Dr P Noakes,
Department of Physiology & Pharmacology, The University of Queensland, QLD

Analysis of subsynaptic distributions of neurotrophins

Dr S Bartlett,
Department of Physiology & Pharmacology, The University of Queensland, QLD

Effect of the disruption of the p75 NGF receptor on neurotrophin transport

Dr P Bartlett,
WEHI, Melbourne, VIC

__________________

Dr C Morgans

Electron microscopic localization of calcium channels in the retina

Dr E Fletcher,
CJ Martin Post-doctoral Fellow, Max-Planck Institue for brain Research Frankfurt, Germany

Distribution of the calcium-binding protein, frequenin, in the retina

Dr A Jeromin,
Mt Sinai Hospital, Canada

__________________

Prof S Redman

Synaptic plasticity

Dr C Stricker,
University of Zurich, Switzerland

Synaptic transmission in the spinal cord

Prof J Jack,
Laboratory of Physiology, Oxford, UK

Membrane properties of motoneurons

Prof Hans Lüscher,
Department of Physiology, University of Bern, Switzerland

__________________

Dr P Sah

Physiological mechanisms underlying startle disease

Dr R Callister,
University of Newcastle, NSW

__________________

Dr G Stuart

Interaction of action potentials and EPSPs in neurons of the CNS

Dr M Häusser,
Dept. Physiology, University College London, UK

__________________

Dr R Taylor

Application of transgenic techniques to study photoreceptor-to-bipolar cell synaptic transmission

Dr R Duvoisin,
Dyson Vision Research Institute at Cornell Medical School, New York, USA

__________________

Dr B Walmsley

Postsynaptic receptor clustering and synaptic efficacy at central synapses

Dr FJ Alvarez and Prof REW Fyffe,
Department of Anatomy, Wright State University

Molecular mechanisms of transmitter release

Prof PR Dunkley, Assoc Prof JAP Rostas, Dr A Slim and Dr S Fieuw-Makaroff,
Discipline of Medical Biochemistry, Faculty of Medicine and Health Sciences, University of Newcastle, NSW