Collaborative Research Ventures

HIGH BLOOD PRESSURE RESEARCH UNIT

Professor JA Whitworth

Gene expression in steroid hypertension
Prof B Morris
Dept of Physiology
University of Sydney, NSW

Micropuncture studies in steroid hypertension
Prof W Anderson and Dr K Denton
Dept of Physiology
Monash University, VIC

Steroid hypertension in humans
Drs J Kelly and G Mangos
Depts of Medicine and Renal Medicine
The St George Hospital
University of New South Wales, NSW

Jason McKenzie working with Paul Foster on asthma research. Photo: JCSMR Photography Haemodynamic consequences of ACTH stimulation tests
Prof R Jackson
Dept of Medicine
University of Queensland, QLD

Cortisol / cortisone shuttle in hypertension
Dr B Walker
Dept of Medicine
Univeristy of Edinburgh, UK

DIVISION OF BIOCHEMISTRY AND MOLECULAR BIOLOGY

Dr MG Casarotto

Structural studies into the mechanism of dihydrofolate reductase
Prof G Roberts
Centre for Mechanisms of Human Toxicity
University of Leicester, UK

Dr J Basran
Department of Biochemistry
University of Leicester, UK

Chitinase and Chitin Binding Proteins
Dr C Vorgias
Biology Department
Athens University, Greece

Prof. H Schrempf
Universitat Osnabruk
FB Biologie/Chemie, Osnabruk Germany

Effects of drugs that block Vpu ion channels studied with NMR techniques
Professor A Watts
Oxford University, Oxford, UK

Professor G Cox

Structure of Fo-F1-ATPase subunits by X-ray crystallography
Dr M Guss
University of Sydney, Sydney NSW

ATP-Synthase mechanism
Professor AE Senior
School Of Medicine & Dentistry
University of Rochester, New York USA

Proton-energised membrane transporters
Professor AJ Pittard
University of Melbourne, VIC

Dr P Foster

Characterisation of the role of eotaxin in the mechanism of pulmonary eosinophilic inflammation
Dr M Rothenberg
Childrens Hospital Medical Centre
University of Cincinnati, USA

The role of triadin in the regulation of ca2+ release from the sarcoplasmic reticulum
Dr P Allen
Brigham & Women's Hospital, Harvard Medical School
Boston, USA

Modeling chronic inflammation in mice
Associate Professor R Kumer
Department of Pathology, University of NSW
Sydney NSW

Role of parasitic infection in the predisposition to allergy
Drs C. Ovington and L. Milburn
Division of Biochemistry And Molecular Biology
The Faculties, ANU

Role of a novel marker for th-2 cells in allergy
Dr T Coyle
Milinium Pharmaceutics Inc, Boston USA

Dr JE Gready, Dr PL Cummins and Dr SP Greatbanks

Development of programs and applications for biomolecular QM/MM calculations
Dr A Rendell
ANU Supercomputer Facility

Dr JE Gready and Mr SJ Titmuss

Development, evaluation and application of the linear-scaling QM method MOZYME for biomolecular calculations
Dr A Rendell and Dr A Bliznyuk
ANU Supercomputer Facility
Dr R Nobes
Fujitsu European Centre for Information Technology, London UK
Dr J Stewart
Stewart Computational Chemistry, Colorado Springs USA

Dr JE Gready and Dr PJ Harvey

Use of NMR to study liver dysfunction in cirrhosis
Prof AJ McLean and Dr D Le Couteur
Canberra Clinical School, University of Sydney

Dr JE Gready, Dr WA King and Dr R Hornig

Computational and bioinformatic studies of the mechanism and evolution of the photosynthetic enzyme, Rubisco
Prof TJ Andrews
Molecular Plant Physiology Group, RSBS

Dr DA Jans

Nuclear localisation of the interferon induced IF16 protein
Dr J Trapani/Dr V Sutton
Austin Research Institute, Heidelberg Melbourne Vic

The ERN signalling pathway
Prof MJ Gething
Department of Biochemistry
University of Melbourne

Nuclear targeting of the serine protease granzyme B in cyctolic mediated apoptosis
Dr J Trapani/Dr V Sutton
Austin Research Institute
Heidelberg Melbourne VIC

Receptor and signal-mediated targeting of plasmid-DNA and photosensitiser molecules to the nucleus of specific cell types with application in gene therapy and cancer phototherapy
Prof A Sobolev
Research Center for Molecular Diagnostics & Therapy Moscow

A regulated nuclear localisation signal in MAP2
Dr K Loveland
Monash Medical Centre
Melbourne VIC

Regulation of nuclear localisation of the Dengue virus NS5 protein
Dr S Vasudevan
James Cook University of North Queenslandqld
(IAS Australian Universities' Research Collaborative Scheme)

Dual nuclear localisation signals of SRY
Dr V. Harley
Howard Florey Institute Parkville VIC

Nuclear targeting pathways for IGFBPs
Dr L Schedlich/Prof R Baxter
Kolling Medical Research Institute, Sydney NSW

Evolutionary aspects of NLS-binding protein sub units and their regulation of nuclear protein import
Prof N Raikhel
Michigan State University
East Lansing, USA

Nuclear targeting by PTHrP
Dr M Gillespie
St Vincent's Institute for Medical Research
Fitzroy, VIC

Interaction of the cellular nuclear import machinery with DNA conjugates for in vivo electroporation
Prof A Pessi
IRBM, Pomezia, Italy

Nuclear transport and function of the granzyme B inhibitor, the serpin PI-9
Dr PI Bird
Dept of Biochemistry and Molecular Biology
Monash University, Melbourne, VIC

Development of chimeric proteins for targeted gene delivery
Dr R Nordon
Biomedical Engineering
University of NSW, NSW

Dr KI Matthaei and Professor IG Young

The role of IL-5 in tumour progression
Dr V Apostolopolous and Professor I McKenzie
Austin Research Institute, Heidelberg, VIC

The role of IL-5 in reproduction
Dr S Robertson
Department of Obstetrics, (Medical School),
The University Of Adelaide, SA

The role of IL-5 in smooth muscle hyperreactivity of the gut
Dr B Vallence and Professor S Collins
Division of Gastroenterology, Department of Medicine,
McMaster University,
Hamilton, Ontario, Canada

The role of IL-5 in mucosal immunity
Dr B Bao and Professor A Husband
Veterinary Pathology,
University of Sydney, NSW

The role of IL-5 and eosinophils in tumour rejection
Dr M Rothenberg
Childrens Hospital Medical Centre
University of Cincinnati
Cincinnati, USA

The role of IL-5 in eosinophil precursor differentiation
Professor J Denburg
Department of Medicine,
McMaster University,
Hamilton, Ontario, Canada.

The role of the mouse homologue of "flightless" in vivo
Dr H Campbell
Molecular Evolution and Systematics, RSBS, ANU

Neuronal development in IL-5 deficient mice
Dr R Egan
Senior Director, Allergy Division,
Shering-Plough Research Institute,
Kenilworth, NI USA

Behavioral studies in IL-5 deficient mice
Dr J Homewood
Psychology Department,
MacQuarie University, Sydney NSW

Hookworm infection in IL-5 deficient mice
Prof P Prociv
Department of Parasitology,
The University of Qld, QLD

Dr KI Matthaei

The role of B2-glyoprotein 1 in vivo
Prof S Krilis
St George's Hospital, Kogarah NSW

Cell surface markers during early development
Dr C O'Neill
Head, Human Reproduction Unit
Royal North Shore Hospital of Sydney
NSW

The roles of MIC-1 and NCC27 in vivo
Dr S Breit
Centre for Immunology, St Vincents Hospital
Darlinghurst NSW

Dr M Frances Shannon

Mechanisms of HMGI(Y) activation of T Cell cytokine genes
Dr R Reeves
Department of Biochemistry and Biophysics
Washington State University
Pullman, WA

Function of the coactivator PC4 in HIV gene transcription (with Dr Adele Holloway)
Dr M Meisterernst
Laboratory of Molecular Biology-Genzentrum
Ludwig-Maximilians-University
Munich, Germany

Dr D Harrich
HIV Research Laboratory
Sir Albert Sakzewski Virus Research Centre
Royal Childrens Hospital, Herston Qld

The role of cold shock domain proteins in cytokine gene transcription
Dr L Coles
Division Of Human Immunology
Hanson Centre for Cancer Research
Adelaide SA

Transgenic models of cytokine gene transcription
Dr P Cockerill
Division of Human Immunology
Hanson Centre for Cancer Research
Adelaide SA

Development of the GM-CSF E21R antagonist
Dr A Lopez and Prof M Vadas
Division of Human Immunology
Hanson Centre for Cancer Research
Adelaide SA

Dr D Shaw

Structure/function of milk proteins
Dr K Bel
Department of Physiology, University of Queensland, Qld

Lactation physiology
Dr KR Nicholas
Victorian Institute of Animal Science
Melbourne, VIC

Human lens proteins
Professor RJW Truscott
Australian Cataract Research Foundation
University of Wollongong, NSW

Immunogolulins
Prof A Edmundson
Oklahoma Medical Research Foundation
Oklahoma City USA

Dr D Tremethick

Function of histone H2AZ in mammalian development
Dr I Lyons
Department of Biochemistry,
University of Adelaide, SA

Establish fly lines required to study the function of H2AZ in Drosophila development
Prof R Saint
Department of Genetics,
University of Adelaide, SA

Solving the cyrstal structure of a H2AZ containing nucleosome
Dr K Luger
Department of Biochemistry and Molecular Biology,
Colorado State University, USA

To examine a possible link between the mode of action of Phenobarbital and chromatin structure
Dr B May
Department of Biochemistry,
University of Adelaide, SA

To investigate whether chromatin structural changes are associated with brain function
Dr J Leah
Biomedical Sciences,
Griffith University, VIC

Gain an understanding of the role of chromatin in the regulation of hepatitis B virus (HBV) gene expression and pathogenesis
Dr J Fyfe
Victorian Infectious Disease Resource Laboratory, VIC

Prof IG Young

Human low molecular weight B cell growth factor.
Dr EM Benson
Department of Medicine, Westmead Hospital, NSW

X-ray structure of the IL-5 receptor
Dr P Carr and Dr D Ollis
Research School of Chemistry, ANU

Professor Angela Dulhunty

Oxidation of ryanodine receptor from malignant hyperthermia pig muscle
Professor R Fink
University of Heidelberg, Heidelberg, Germany

Structure of dhpr binding domain on ryanodine receptor calcium release channel
Dr D McClennan
Banting & Best Research Institute, Toronto, Canada

Ultrastructural location of triadin in dyspedic mouse muscle
Dr P Allan
Harvard Medical School, Boston USA

Effect of ph on skeletal muscle ryanodine receptor
Dr G D Lamb
La Trobe University, VIC

Effect of ph on skeletal muscle ryanodine receptor
Dr D R Laver
BAMBI, ANU

Ryanodine receptor activation
Dr D R Laver
BAMBI, ANU

Activation of malignant hyperthermic pig muscle
Professor Esther Gallant
Univerity of Minnesota, USA

Professor P Gage

Effects of Conotoxins on Sodium Currents
Professor David Adams
Department of Physiology and Pharmacology
University of Queensland

Structure of The GABA_A Receptor
Dr Michael Parker
St Vincents Hospital, Institute of Medical Research
Fitzroy, VIC

Analysis of Subconductance States in Ligand-Gated Receptors
Dr Shin-Ho Chung
Dept of Chemistry, ANU

Effects of drugs that block Vpu ion channels on AIDS Virus replication
Professor Tony Cunningham and Dr Hassan Naif
Westmead Hospital NSW

Structure of Vpu ion channels studied with NMR techniques
Professor Tony Watts
Oxford

DIVISION OF IMMUNOLOGY AND CELL BIOLOGY

Dr J. Banyer

Determination of genetic factors responsible for multi-drug resistance in small cell lung carcinoma

Dr R Davey
Clinical Oncology, Royal North Shore Hospital, Sydney, NSW

Genetic differences between subsets of human NK cells
Dr H. Warren
Canberra Hospital,
Canberra, ACT

Drs J Banyer and AJ Hapel

Identification and charcterisation of immunoregulatory genes from dendritic cells
Drs J Tite and M Goulden
Glaxo-Wellcome Ltd,
Stevenage, UK

Comparative analysis of genetic determinants characteristic of ex vivo isolated dendritic cells and myb-transformed MTHC-derived dendritic cells

Dr I Caminischi and Professor K Shortman
The Walter and Eliza Hall Institute,
Melbourne, VIC

Drs J Tite and M Goulden
Glaxo-Wellcome Ltd,
Stevenage, UK

Professor RV Blanden and Dr C Bruce

Mechanisms of somatic variation of V genes
Dr EJ Steele
University of Wollongong,
Wollongong, NSW

Evolutionary origin of germline V genes in the immune system
Dr EJ Steele
University of Wollongong,
Wollongong, NSW

Dr G Weiller
Research School of Biological Sciences,
ANU

Dr IA Clark

The role of nitric oxide in the pathogenesis of falciparum malaria
Dr Malcolm Molyneux
Wellcome Trust Centre
Blantyre
Malawi

Dr Terri Taylor
Dept. of Internal Medicine
College of Medicine
Michigan State University
USA

Dr Richard Carr
St Thomas's Hospital
London, UK

Dr Kirk Rockett
Dept of Paediatrics
University of Oxford
John Radcliffe Hospital
Oxford, UK

Dr P Cooper

Adjuvant activity of gamma inulin
Dr P. Goldwater
Adelaide Children's Hospital
Adelaide, SA

Professor I Frazer and Dr R Tindle
Princess Alexandra Hospital,
Brisbane, Qld

Dr R Gupta
Massachusetts Public Health,
Biological Laboratories,
Boston, MA, USA

Dr Frederick Vogel
AIDS Vaccine Research Branch,
NIH, Bethesda, USA

Dr P Fuentes
Universitat Autonoma de Barcelona,
Barcelona, Spain

Dr G Guillen
Centre for Genetic Engineering & Biotechnology,
Havana, Cuba

Dr DO Willenborg
Neurosciences Research Unit,
Canberra Hospital,
Canberra, ACT

Dr Irit Pinchasi
TEVA Pharmaceutical Industries
Israel

Dr Garcon
Smithkline Beecham,
Rixensart, Belgium

Profesor G Tannock
Royal Melbourne Institute of Technology,
Melbourne, VIC

Dr E Depla
Innogenetics NV,
Ghent, Belgium

Dr P Birk
M & E Biotech A/S,
Horsholm, Denmark

Dr WB Cowden

The role of nitric oxide in autoimmune disease
Dr K Rockett
Institute of Molecular Medicine,
John Radcliffe Hospital,
Oxford, UK.

The role free radicals in vascular disease
Dr Roland Stocker
The Heart Research Institute,
Sydney, NSW

The activity and mechanism of action of novel glycoprotein processing inhibitor anti-rejection agents
Professor Adrien Hibberd
Hunter Valley Hospital Transplant Unit,
Newcastle, NSW

Novel approaches to immunisation
Dr Alistair Ramsay
Newcastle University,
Newcastle NSW

Dr AJ Hapel

Analysis of the role of interleukin-3 and CSF-1 in synergistic signalling by targetting of their receptor genes
Professor ER Stanley
Albert Einstein College of Medicine,
New York, USA

Targetted dissruption of the c-fms gene
Professor ER Stanley
Albert Einstein College of Medicine,
New York, USA

Mechanism of cell death in Ross-River virus-infected striated muscle
Dr Brett Lidbury
University of Canberra,
Canberra, ACT

Drs AJ Hapel and J Banyer

Differentiation of myb-transformed haematopoietic progenitor cells
Assoc. Professor T Gonda
Hanson Centre for Cancer Research,
Adelaide, SA.

Drs J Tite and M Goulden
Glaxo-Wellcome Ltd,
Stevenage, U.K.

Isolation of Ross-River virus resistance genes from macrophage "RAW" cells
Dr Brett Lidbury
University of Canberra,
Canberra, ACT

Dr M Hulett

Cloning and characterisation of a novel family of tetraspan molecules
Dr M Cancilla
The Walter and Eliza Hall Institute of Medical Research,
Melbourne, VIC

Dr T Luft
Ludwig Institute for Cancer Research,
Melbourne, VIC

Dr M Hogarth
Austin Research Institute,
Melbourne, VIC

Dr P Dacey and Dr M Smyth
Austin Research Institute,
Melbourne, VIC

Dr S Russell
Austin Research Institute, Melbourne, VIC

Dr L Baker and Professor G Sutherland
Women's and Children's Hospital,
Adelaide, S.A.

Structure and function of Fc Receptors
Dr M Hogarth and Dr B Wines
Austin Research Institute,
Melbourne, VIC

Dr M Lobigs

Protective immune responses in mice vaccinated with recombinant vectors expressing flavivirus genes
Dr RA Hall and Professor J Mackenzie
Department of Microbiology,
University of Queensland,
Brisbane, Qld

Selectivity in peptide translocation by Syrian hamster TAP
Drs F Momburg and Professor G. Hämmerling
German Cancer Research Center,
Heidelberg, Germany

Modulation of the MHC class I antigen processing and presentation pathway by flaviviral infection
Dr. F Momburg
German Cancer Research Center,
Heidelberg, Germany

Structural polyprotein processing mutants of yellow fever virus, 17D, generated from an infectious cDNA clone
Professor CM Rice
Washington University School of Medicine,
St. Louis, USA

Dr A Müllbacher

Oral induced T cell tolerance
Dr James Chin
Elizabeth MacArthur AG Institute,
NSW Department of Agriculture,
Camden, NSW

The role of granzyme A in fungal infection
Dr R Ashman
Oral Biology and Pathology,
University of Queensland,
Brisbane, Qld

The role of granzymes and perforin in cytomegalovirus infections
Dr S Landolfo
Department of Public Health,
Medical School,
Turin, Italy

The role of granzymes in herpes virus infection
Drs R Pereira and A Simmons
Herpes Research,
Infectious Diseases Laboratories,
Institute of Medical & Veterinary Science,
Adelaide, SA

Drs A Müllbacher and M Lobigs

The role of T cell serine proteases in cell cytotoxicity and viral pathogenesis
Dr M Simon
Max Planck Institute für Immunbiologie,
Freiburg, Germany

Allorecognition
Dr R Langman,
Conceptual Immunology,
The Salk Institute,
La Jolla, CA, USA

Drs A Müllbacher, M Lobigs and Professor RV Blanden

The role of MHC-class I in antigen presentation
Dr Jon Yewdell
Viral Immunology Laboratory,
National Institute of Allergy and Infection Diseases,
National Institutes of Health,
Bethesda, USA

Drs A Müllbacher and P Waring

The role of poxvirus encoded serpins in cytotoxic T cell induced apoptosis
Dr R Wallich
Department of Immunology,
University of Heidelberg,
Heidelberg, Germany

The role of granzymes in the induction of apoptosis
Dr M Simon
Max Planck Institute fur Immunbiologie,
Freiburg, Germany

Professor C Parish

Sulfated oligosaccharides as anti-viral agents
Dr A. Cunningham
Westmead Hospital,
Sydney, NSW

Inhibition of uveitis by oligosaccharides
Dr K Williams
Flinders Medical Centre,
Bedford Park, SA

Carbohydrate-based anti-metastatic compounds
Dr R Anderson
Peter MacCallum Cancer Institute,
Melbourne, VIC

Drs H Wheeler and N Pavlakis
Royal North Shore Hospital,
Sydney, NSW

Analysis of cell adhesion molecules on human lymphocytes
Dr H Warren
Canberra Hospital,
Canberra, ACT

Novel multimeric technology for cell surface molecules
Dr B Cornell
AMBRI,
Sydney, NSW

Dr J Altin
Biochemistry and Molecular Biology Division,
The Faculties,
ANU

Histidine-rich glycoprotein deficiencies and autoimmune disease
Professor P Gatenby
Canberra Hospital,
Canberra, ACT

Development of pseudo-oligosaccharides as heparan sulfate mimetics
Professor M Banwell
Research School of Chemistry,
ANU

3D structure of mammalian heparanase
Dr M Parker,
St Vincents Hospital,
Melbourne, VIC

Role of histidine-rich glycoprotein in angiostatin formation and action
Dr P Hogg
School of Pathology,
University of New South Wales,
Sydney, NSW

Dr A Ramsay

Cytokines and dendritic cells in oral tolerance and mucosal immune responses, and non-replicating oral vaccines for immunocontraception
Dr K.W. Beagley
University of Newcastle,
Newcastle, NSW

Recombinant poxvirus-based immuno-contraceptive vaccine development
Dr R Jackson
Division of Wildlife and Ecology,
CSIRO,
Gungahlin, ACT

Genetic vaccine strategies for mucosal immunity against HIV
Dr S Kent
MacFarlane Burnet Centre,
Melbourne, VIC

Professor IA Ramshaw

Design of viruses for the biological control of vertebrate populations
Drs R Jackson and P.Kerr
Division of Wildlife and Ecology,
CSIRO,
Canberra, ACT

Investigation into immunogenicity of DNA vaccines
Professor H Robinson
Department of Pathology,
University of Massachusetts,
Worcester, MA. USA

The use of vaccinia virus expressing IL-2 in the treatment of lung cancer
Professor B Robinson
Sir Charles Gardner Hospital,
Nedlands, WA

HIV polytope vaccines
Dr A Suhrbier
QIMR,
Brisbane, Q'ld

Dr R. Ffrench
Westmead Hospital,
Westmead, NSW

Dr S Thomson

Polyepitope vaccine for Papilloma virus infection and cervical cancer
Assoc. Prof B Tindle
Sir Albert Sakzewski Virus Research Centre,
Brisbane Qld

Polyepitopes to treat Burkitt's lymphoma and glandular fever
Professor D Moss, Drs R Khanna and M Sherritt
Queensland Institute of Medical Research
Brisbane Qld

Drs S Thomson, W Cowden and Professor IA Ramshaw

Delivery of multiple EAE epitopes
Dr D. O. Willenborg
Neurosciences Research Unit,
Canberra Hospital,
Canberra ACT

Drs S Thomson and G Karupiah

Recombinant ectromelia viruses expressing immune modulating antigens
Dr N Davis-Poynter
Department of Microbiology,
University of Western Australia,
Nedlands, WA

Dr P Waring

Structure activity studies of naturally occurring and synthetic members of the epipolythiodioxopiperazine class of immunomodulating fungal toxins
Dr Christine Chai
Chemistry, The Faculties,
ANU

Cell cycle analysis as a tool for the determination of nutritional status in fish
Dr John Kalish
BOZO, The Faculties,
ANU

The measurement of oestrogenic activity of pollutants in local water supplies
Dr John Kalish
BOZO, The Faculties,
ANU

The biological activity and effects on mitochondrial function of gold phosphine complexes and their clinical potential as antiproliferative agents
Dr Geoff Salem
Chemistry, The Faculties,
ANU

The activity of the Calothrixin toxins
Dr Geoff Smith
BAMBI, The Faculties,
ANU

DIVISION OF MOLECULAR MEDICINE

Dr N G Ardlie

Influence of fatty acid content on the oxidisability of LDL in subjects with coronary artery disease
Dr D A McGill
Department of Cardiology, The Canberra Hospital, ACT

Low density lipoprotein oxidation in haemochromatosis
Dr M L Bassett
Department of Gasteroenterology, The Canberra Hospital, ACT
&
Dr J E Dalhstrom and Dr S Jain
Department of Anatomical Pathology, The Canberra Hospital, ACT

Dr RT Baker

Role of the Drosophila deubiquitylating enzyme Fat Facets in eye development
Dr J Fischer
Dept of Zoology
U Texas, Austin, USA

Yeast ribosomal protein genes
Prof REH Wettenhall
The Russell Grimwade School of Biochemistry and Molecular Biology
University of Melbourne, VIC

Biochemistry and molecular genetics of the mouse protooncogene Unp
Dr D Gray
University of Ottawa, Ottawa, Ontario, Canada

Identification and characterisation of novel chicken deubiquitylating enzymes
Prof Chin Ha Chung
Seoul National University, Korea

Phylogenetic and evolutionary studies of the ubiquitin-specific protease family
Dr LS Jermiin
School of Biological Sciences, University of Sydney

Mapping human and mouse genes to chromosomal locations
Prof G Sutherland
Women's and Children's Hospital, Adelaide
&
Dr N Copeland
Mammalian Genetics Laboratory
NCI-FCRC, Frederick, MD USA

Professor P Board

Structural analysis of glutathione S-transferases
Dr M Parker
St Vincent's Medical Research Institute
Melbourne, VIC

Regulation of mouse Theta class GST genes
Dr W Pearson
Department of Biochemistry, School of Medicine
University of Virginia Health Sciences Center
Charlottesville, Virginia USA

Use of GST genes to create drug resistance in hematopoietic stem cells
Dr M Webb
Haematology, The Canberra Hospital, ACT

Structural analysis of the Omega class GSTs
Dr C Gabel, Dr K Geoghegan and Dr J Pandit
Central Research Division, Pfizer Inc, Groton CT, USA

Phylogenetic and evolutionary studies of the glutathione S-transferase family
Dr LS Jermiin
School of Biological Sciences, University of Sydney

Parkinson's Disease, Pesticides and glutathione transferase polymorphisms
Dr D LeCouteur
Department of Pharmacology, University of Sydney
and Canberra Clincal School, The Canberra Hospital, ACT

Function of the Zeta class GSTs
Dr MW Anders
Dept. of Pharmacology and Physiology, University of Rochester Medical

Functional analysis of glutathione transferases
Dr M Lo Bello, Dr A Caccuri and Dr G Ricci
University of Rome

Dr S. Easteal

The genetic basis of common mental disorders associated with anxiety and depression
Prof AS Henderson and Dr A Jorm
Social Psychiatry Research Unit, ANU
&
Prof M Prior
Psychology Department, Melbourne University

Genetics and Evolution of human alpha actinin-3
Drs KN North and N Yang
Neurogenetics Research Unit, Royal Alexandra Hospital for Children, Sydney
&
Dr AH Beggs
Harvard Medical School, Boston

Development of methods for analysing the evolution of multigene families
Prof S Wilson
School of Mathematical Sciences, ANU

Development of ultrafast maximum likelihood programs forDNA and protein sequence analysis on supercomputers
Dr M Kahn
The ANU Supercomputer Facility, ANU
&
Dr R Brown
The ANU Supercomputer Facility, ANU
&
Dr BD McKay
Department of Computer Science, ANU
&
Dr MJ Wolf
Computer and Information Science Department, Mankato State University, USA
&
Dr L Jermiin
Australian Genomic Information Centre, The University of Sydney

Analysis of ancient human DNA
Dr A Thorne
Department of Prehistory and Anthropology, ANU
&
Drs J Peacock and E Dennis
CSIRO Division of Plant Industry
&
Dr L Jermiin
Australian Genomic Information Centre, The University of Sydney

Dr G Chelvanayagam

Peptide epitopes
Dr V Apostolopoulos & Prof IFC McKenzie
The Austin Research Institute, Heidelberg, Vic

Structure functions and mechanisms of GSTs
A/Prof M Parker
St Vincent's Institute of Medical Research, Melbourne, Vic

Functional properties of HLA molecules
Dr X Gao
National Cancer Institute, Frederick MD USA

MHC molecules as proteases
Dr M Lobigs & Dr A Mullbacher
JCSMR

Protein structure
Prof GH Gonnet
ETH, Zuriich Switzerland
&
Prof SA Benner
Dept. Chemistry
University of Florida USA

Dr G.A. Huttley

Comparative evolutionary analysis of the HLA and other genomic regions
Dr G Thomson
Department of Integrative Biology, UC Berkley, USA

Assessing concordant equilibria of case and control populations
Prof SR Wilson
School of Mathematical Sciences, ANU

Assessing the utility of SNP markers for linkage disequilibrium mapping
Prof D Naiman
Dept. of Mathematical Sciences, John Hopkins University, Baltimore MD, USA
&
Prof G Uhl
School of Medicine, John Hopkins University
&
Prof SR Wilson
School of Mathematical Sciences, ANU

Dr GA Huttley and Dr S Easteal

Analysis of genetic diversity at cancer susceptibility genes in humans and other primates
Dr DJ Venter
Peter MacCallum Cancer Institute, Melbourne
&
Dr J L Hopper
Centre for Genetic Epidemiology, University of Melbourne

Assessing the importance of DNA replication on mutation
Prof SR Wilson
School of Mathematical Sciences, ANU

Dr I Jakobsen
Institute for Molecular Evolution, Pennsylvania State University, USA

The effect of varying demographic and evolutionary regimes on patterns of linkage disequilibrium
Prof SR Wilson
School of Mathematical Sciences, ANU

Prof C Goodnow

Genetic analysis of B cell development and activation (supported by the Human Frontiers Science Program)
Dr M Thomas
Dept of Pathology, Washington University
St. Louis, MO USA
&
Prof K Rajewsky
Institute for Genetics, University of Cologne
Germany

Role of CD22 and interactions with SHP-1 phosphatase in B cells
Dr E Clark
University of Washington, Seattle WA USA

Gene expression during B cell activation, anergy and immunosuppression
Dr D Mack
Affymetrix Inc, Santa Clara
California

Genetic modifiers of squamous carcinogenesis
Dr D Hanahan
University of California, San Francisco
&
Dr S Foote
Walter and Eliza Hall Institute, Melbourne

Discovery of new mutations affecting blood cell formation
Dr D Hilton and Dr W Alexander
Walter and Eliza Hall Institute, Melbourne

Dicsovery of new mutations affecting breast duct proliferation
Dr C Ormandy
Garvan Institute, Sydney

Discovery of new mutations affecting bone and soft tissue mass
Dr E Gardiner
Garvan Institute, Sydney

Discovery of new mutations affecting splenic architecture
Dr J Cyster
University of California, San Francisco

Discovery of new mutations affecting behaviour and coordination
Dr C Fletcher and Dr S Kay
Novartis Institute of Functional Genomics, San Diego

Development of high-throughput methods for screening ENU and other mouse mutant libraries
Dr M Chee
Illumina Inc, San Diego

Dr M Kohonen-Corish

Genetic susceptibility to human colorectal cancer
Prof WF Doe
University of Birmingham Medical School, UK
&
Dr J St John and Dr F Macrae
Royal Melbourne Hospital
&
Dr J Wijnen and Dr R Fodde
University of Leiden, the Netherlands
&
Prof L Bokey, Prof P Chapuis and Prof R Newland
Concord Hospital, Sydney

Molecular Genetics of Melanoma and Lung Cancer
Dr M Millward
Sydney Cancer Centre, Sydney
&
Prof R Trent
Department of Molecular and Clinical Genetics
Royal Prince Alfred Hospital, Sydney

Cancer-colitis model in Msh2 deficient mice
Dr G Buffinton
St. Bartholomew's and Royal London School of Medicine and Dentistry
London, UK
&
Dr J Dahlstrom
The Canberra Hospital
Dr H te Riele
The Netherlands Cancer Institute, Amsterdam, the Netherlands

Dr P McCullagh

Investigation of X maturation of the ileal Peyer's patches
Prof C Press and T Landsverk
Royal Norwegian Veterinary School, Oslo

Development of Peyer's patches and of immunological function in the gut of the fetal lamb
Dr S McClure
McMaster Laboratory, CSIRO, Sydney

Compartmental modelling of lymphocyte migration
Dr L Dedik
Faculty of Mechanical Engineering
Slovak Technological University, Bratislava.

Compartmental modelling of lymphocyte migration
Dr M Durisova
Institute of Experimental Pharmacology
Slovak Academy of Sciences, Bratislava

System analysis of lymphocyte migration
Dr F De Bruyne
Research School of Engineering and Information Science, ANU

Pulmonary development in thyroidectomized fetal lambs
Dr M Peek
Fetal Medicine Unit, Department of Obstetrics
University of Sydney, Canberra Clinical School, ACT

Electron microscopic examination of the alveoli of athyroid fetal lambs
Dr J Dahlstrom
Pathology Department
The Canberra Hospital, ACT

Dr CJ Simeonovic

Neuroprogenitor cells for delivery of immunoregulatory cytokine genes to pig proislet xenografts in mice
Dr R Taylor
Dept of Animal Science
University of Sydney, NSW
&
Clin Assoc Prof JD Wilson
Department of Endocrinology
The Canberra Hospital, ACT

Regulation of pig proislet xenograft destruction and assessment of the potential for xenozoonoses
Prof A Gibbs
Molecular Genetics and Evolution
Research School of Biological Sciences
&
Clin Assoc Prof JD Wilson
Department of Endocrinology
The Canberra Hospital, ACT

Role of chemokines in the rejection of pig proislet xenografts
Dr WA Kuziel
Section of Molecular Genetics and Microbiology
The University of Texas at Austin
Austin, Texas, USA

Macrophage-induced muscle pathology following Ross River Virus - infection in mice
Dr B Lidbury
Gadi Research Centre
Division of Science and Design
University of Canberra, ACT

DIVISION OF NEUROSCIENCE

Dr JM Bekkers

Single-channel properties of the slow AHP current
Professor Bert Sakmann
Max Planck Institute for Medical Research, Heidelberg

Dr M Crouch

PI 3-kinase
Dr Paul Naccache
University of Quebec, Canada

Flightless I protein
Dr Hugh Campbell
RSBS, ANU

Growth factor signal transduction
Dr Bruce Kemp
St. Vincent's Institute of Medical Research, Melbourne;
Dr Richard Pearson
Peter MacCallum Cancer Institute, Melbourne

Protein kinase G
Dr Phillip Robinson
Children's Medical Research Institute, Sydney

Dr CE Hill

Electrical properties of iridial arterioles of the rat
Drs GDS Hirst, FR Edwards
Department of Zoology, University of Melbourne

Professor IA Hendry

Neuromuscular growth factors
Dr Ian MacLennan
Department of Anatomy, University of Otago

Investigating the Role of Neurotrophins and their Receptors at the Neuromuscular Synapse
Dr Peter Noakes and Dr Selena Bartlett
Department of Physiology & Pharmacology, The University of Queensland

PI4-kinase and NCS-1 co-localize in the growth cones of cultured mouse neurons
A Jeromin, J Roder
Mount Sinai Hospital, University of Toronto, Canada

Localisation of the mouse small optic lobe protein (sol) in the olfactory bulb
Dr Alan Mackay-Sim
Griffith University

The neurotrophic factors involved in retinal ganglion neuronal survival
Dr Alan Harvey
University of Western Australia

Dr G Stuart

Interactions of EPSPs and action potentials
Dr Michael Hausser
University College London

Dr P Sah

Physiological mechanisms underlying startle disease
Dr Robert Callister
University of Newcastle

Dr B Walmsley

Postsynaptic receptor clustering and synaptic efficacy at central synapses
Dr FJ Alvarez and Professor REW Fyffe
Department of Anatomy, Wright State University

Molecular mechanisms of transmitter release
Professor PR Dunkley; Associate Professor JAP Rostas; Dr A Slim and Dr S Fieuw-Makaroff
Discipline of Medical Biochemistry, Faculty of Medicine and Health Sciences, University of Newcastle

Dr WR Taylor

Direction selectivity in the rabbit retina
Dr DI Vaney & Dr S He
Vision, Touch and Hearing Research Centre, University of Queensland

Mecahnisms of colour vision in the wallaby retina
Dr J Hemmi & Dr R Mark
RSBS, ANU

Professor SJ Redman

Synaptic transmission between interneurones and motoneurones in spinal cord
Professor Julian Jack
Oxford

Serial correlation in release probability
Dr C. Stricker
University of Zurich