Grants                                                 

Biochemistry and Molecular Biology | High Blood Pressure Research
Immunology and Cell Biology | Molecular Medicine | Neuroscience

NB: Grant monies are for the year 2000, unless otherwise specified.

Biochemistry and Molecular Biology

$634,000 The Wellcome Trust To Dr F Shannon, Prof C Goodnow, Prof D Jans, Dr R Baker, Dr D Tremethick For purchase of a microarray system. $220,666 ($662,000 2000/2003) Juvenile Diabetes Foundation International To Dr R Slattery $113,570 NHMRC (2000-2002 ) To Prof AJ McLean and Dr PJ Harvey (Canberra Clinical School) and DrJE Gready Assessment of hypoxia and hepatic metabolism in cirrhotic ratsusing NMR.

Dr Robyn Slattery with Lab Assistant Jennifer Kofler

$30,000
ARC/DETYA SPIRT (APAI) (1998-2000)
To Dr JE Gready, Dr AP Rendell and Dr R Nobes
Application of linear scaling semi-empirical quantum chemical methodsto the study of enzyme reaction mechanisms.

$35,000
APAC Centre of Expertise Program (2000-2003)
To Dr JE Gready
Biomolecular simulation and bioinformatics.

$17,800
Australian Society for Blood Transfusion Research Fund)
To Dr JE Gready and Dr Minchinton
(Australian Red Cross Blood Service, Brisbane)
Screening of therapeutic potential of mannose-binding lectins againstpathogens using bioinformatic and molecular modellingmethods.

$40,000
ARC Postdoctoral Fellowship (1997-2001)
To Dr RK Schmidt
Hybrid quantum mechanical and molecular mechanical studies of thereaction mechanism of lactate and malate dehydrogenases

$44,000
DAAD (Deutscher Akademischer Austauschdienst) Fellowship (2000-2001)
To Dr H Mauser
Computational dissection of the multi-step reaction mechanism of Rubisco

$267,000
ARC - RIEF scheme
To Prof. DA Jans
For Confocal laser scanning microscope

$12,000
The Rebecca L. Cooper Medical Research Foundation Ltd
To Dr MHC Lam and Prof DA Jans
For Gene transfer technologies

$92,000 ($276,000 2000/2002)
ARC Large Project Grant
To Prof. M-J Gething and Prof DA Jans
For nuclear import of the Ern1 receptor kinase regulates activation of the unfolded protein stress response in Saccharomyces cerevisiae.

$90,000 ($270,000 2000/2002)
ARC-DEETYA SPIRT Grant
To Drs RE Nordon, PJ Simmons, Prof DA Jans and Dr T Lockett
For Development of chimeric proteins for targeted gene delivery

$68,607 ($205,823 2000/2002)
NHMRC CARG Project Grant
To Prof DA Jans
For Regulation of nuclear import of HIV-1 proteins - Implications for therapeutic approaches.

c$600,000 ($627,981 2000/2001)
The Wellcome Trust
To Profs DA Jans, C Parish and Drs DJ Tremethick, P Foster & M Crouch
For Multi-Photon Confocal Upgrade

$15,000
Ramaciotti Foundation Grant
To Dr Shannon and Dr Holloway
The purchase of 2D gel electrophoresis equipment

US$115,000 ($345,000 (US) 2000/2003)
Human Frontier Research Grant
To Dr K Luger and Dr D Tremethick
The molecular function of an essential histone variant

$23,500
Motor Neurone Disease Research Institute of Australia Inc
Dr AKM Hammarström
Persistent sodium channels in SOD-1 mice: a new target for ALS treatment?

$273,259
The Wellcome Trust (Equipment Grant)
To Prof A F Dulhunty, Prof P Board, Dr M Casarotto, Dr Derek Laver (BAMBI); Dr G Lamb, Dr Stephenson (La Trobe)
For Stopped-Flow Spectrophotometer

$120,000
Human Frontier Science Grant
Dr P Foster

High Blood Pressure Research Unit

$57,000

Uniseed
DJ Torpy, AW Bachmann, JA Whitworth, RV Jackson
CBG Gene mutations in Chronic Fatigue Syndrome

$15,000
Clive and Vera Ramaciotti Foundations
Prof JA Whitworth, Dr C Schyvens
Glucocorticoid-induced hypertension in the mouse

 

Immunology and Cell Biology

$375,000 (per year 2000-2003)
Praxis Pharmaceuticals Pty Ltd
To Drs WB Cowden and B Charlton
Investigation of phosphosugars as anti-inflammatory drugs

$61,932 (per year 1999-2001)
ARC
To Professor J Elix, Drs C Chai and P Waring
New lichen metabolites: The isolation, synthesis and biological activities of scabrosin esters and related compounds

$255,835 (per year 1999-2001)
( transferred to Research School of Chemistry July 2000)
GlaxoWellcome
To Dr AJ Hapel
Isolation of novel immunoregulatory genes from dendritic cells

$7,759
Australian Academy of Science Scientific visits to Europe Program
To Dr M Lobigs

$196,000
NSW Cancer Council
To Professor CR Parish, Dr J Altin (BaMBi), Dr P Hogg (UNSW) and Professor C Chesterman (UNSW)
Tumour angiogenesis

$672,000
Progen Industries Ltd
To Professor CR Parish and Professor M. Banwell (Research School of Chemistry)
Development of novel heparinoid mimetics and investigation of the heparanase enzyme as a diagnostic and therapeutic target

$300,000
National Centre for HIV Research
To Professor I Ramshaw and S Thomson
Genetic vaccine strategies for virus infections

$376,000 (per year 2000-2004)
National Institutes of Health
To Professor IA Ramshaw and Dr S Thomson

$60,000
Canberra Hospital Private Practice Fund
To Professor IA Ramshaw and Dr P Craft
Immunotherapy of Cancer

$196,278
NHMRC (971000)
To Dr HS Warren
Human NK cell proliferation: Receptors, ligands and role in inflammation

$18,676
The Canberra Hospital Private Practice fund
To Drs HS Warren and J Wang
Detecting novel human NK cell genes regulating proliferation and function

$160,000 (per year 1999-2003)
NHMRC
To Dr DO Willenborg
The role of interferon-gamma and nitric oxide in the downregulation of central nervous system inflammation

$35,000 (per year 1999 and 2000)
The Canberra Hospital Private Practice fund
To Drs DO Willenborg, MA Staykova and P Cooper
A study to assess the ability of clinically acceptable immune modulators to augement the therapeutic effect of Copolymer-1 in the treatment of an animal model of multiple sclerosis

$30,000 (per year 1999 and 2000)
National Multiple Sclerosis Society of Australia
To Drs DO Willenborg, MA Staykova and P Cooper
A study to assess the ability of clinically acceptable immune modulators to augement the therapeutic effect of Copolymer-1 in the treatment of an animal model of multiple sclerosis

Molecular Medicine

US$176,920
US Nation(al Institutes of Health, NIAID
To C Goodnow
Mechanisms regulating islet cell destruction by CD4 T cells

US$95,727
US National Institutes of Health, NCI
Prof C Goodnow, Dr Dhanahan, Dr S Foote
Identification of genetic modifier loci that influence squamous carcinogenesis elicited by the human papillomavirus type 16 oncogenes in transgenic mice

AUD$400,000
Novartis Institute of Functional Genomics, Collaborative Contract Novartis Foundation.
Prof C Goodnow
Identification and mapping of neurological mutants in mice

US$143,200
US National Institutes of Health, NCI
To Prof C Goodnow, Dr M Chee
Protein Profiling arrays

CA$33,000
Medical Research Council of Canada Postdoctoral Fellowship
To Dr S Lesage

US$80,000
Human Frontiers Science Program RG0311/1997-M
To Prof C Goodnow:
Genetic analysis of B cell differentiation and activation

US$33,000
Human Frontiers Science Program
Postdoctoral Fellowship to Dr Mathieu Blery

US$354,205
U.S. National Cancer Institute Research Consortium
To Prof C Goodnow:
(Co-investigator with Dr S Foote and Dr D Hanahan)
Identification of genetic modifier loci that influence squamous carcinogenesis elicited by the human papillomavirus type 16 oncogenes in transgenic mice

US$ 99,795
Juvenile Diabetes Foundation InternationalNew York)
To Dr C.J. Simeonovic, Clin. Assoc. Prof. J.D. Wilson, Prof. I. Ramshaw, Dr R. Taylor
Neuroprogenitor cells for delivery of immunoregulatory cytokine genes to pig proislet xenografts in mice

$129,850
NHMRC /JDFA/ JDFI Diabetes Collaborative Research Grant
To Dr CJ Simeonovic, Prof I Ramshaw, Dr W Cowden and Clin Assoc Prof JD Wilson
Regulation of the immune response to allografts of adult pancreatic islets

US$100,000
Juvenile Diabetes Foundation International (New York)
To Dr CJ Simeonovic, Clin Assoc Prof JD Wilson, Dr PJ Milburn, Prof A Gibbs.
Regulation of pig proislet xenograft destruction and assessment of the potential for xenozoonos

150,000 FFr ($39,000AUD)
From Ligue Nationale Contre le Cancer (France)
Postdoctoral Fellowship
To C Angelats
The role of the mouse/human oncogen UNP, and its homologue USP15, in the regulation of cell growth and ubiquitin-dependent proteolysis

$158,000
Pfizer Central Research
To Prof P Board with Dr A Dulhuntry and Professor P Gage

 

Neuroscience

$70,000 ($210,000 1999-2001)
NHMRC
To Dr S Bartlett & Dr P Noakes, University of Queensland

$140,000 ($700,000 1998-2002)
Wellcome Trust Senior Research Fellowship
To Dr G Stuart

$21,042 ($84,169 1997-2000)
NHMRC Project Grant
To Dr WR Taylor and Dr DI Vaney, University of Queensland

$35,000 ($70,000 2000-2001)
National Institute of Health
To Dr R Taylor

$20,000
Ramaciotti Foundation
To Professor I Hendry & Dr S Bartlett

$18,000
Motor Neurone Disease Institute of Australia
To Dr S Bartlett & Professor I Hendry

$44,550 ($89,100 2000-2001)
Heart Foundation Research Grant
To Dr C Hill