JCSMR Annual Report 2003 - John Curtin School of Medical Research

Invited Presentations

RT Baker

Regulation of ubiquitin-dependent processes by deubiquitination
Hunter Valley Cell Signalling Meeting, Hunter Valley, NSW

Regulation of ubiquitin-dependent processes by deubiquitination
School of Biotechnology and Biomolecular Sciences, UNSW, Sydney, NSW

Ubiquitin-specific protease 2 isoform 69 interacts with and regulates ubiquitination and trafficking of the
pro-apoptotic ras effector RASSF1C
42nd Annual Conference, ASMR, Adelaide, SA

Proteases in Biology and Medicine
Combio2003, Melbourne, VIC

J Bekkers

Synaptic processing in cultured, sliced and intact brains
Biomedical Sciences, University of Newcastle, Newcastle, NSW

Synaptic transmission and integration in simplified neurons
Neuroscience Program, University of Colorado Health Sciences Center, Denver, USA

In vitro recordings from cultured neurons
Prince of Wales Medical Research Institute, University of New South Wales, Sydney, NSW

Synaptic transmission in olfactory cortex
Eccles Centenary Symposium, Canberra, ACT

E Bertram

Role of 4-1BB receptor in influenza-specific T cell co-stimulation
Microbiology and Immunology discipline seminar, Division of Molecular Bioscience,
The University of Adelaide, Adelaide, SA

A switch in costimulation from CD28 to 4-1BB during primary versus secondary CD8 T
cell response to influenza in vivo
Australasian Society of Immunology meeting, Perth, WA

H Booth

Standardization of Sequence Alignment Scores
APAC2003, Gold Coast, QLD

Normalizing sequence alignment scores for composition bias
Imperial College, London, UK

Normalizing sequence alignment scores for composition bias
RECOMB2003, Berlin, Germany

An iterative approach to the longest common subsequence problem
RECOMB2003, Berlin, Germany

Fractal-like Structure in the Statistics of DNA Sequence Comparison
46th Annual Meeting of the Australian Mathematical Society, AustMS

Voyage along the Human Genome
2003 Australian Festival of Science, Canberra, ACT

J Clements

Non-equilibrium transmitterreceptor binding
Eccles Centenary Symposium, Canberra, ACT

AF Dulhunty

Excitation – Contraction Coupling
2003 Gordon Conference, USA

Calcium release and cellular calcium signalling domains
2003 Workshop, Chile

Genome Diversity and Health
APEC Technology Foresight meeting, Bangkok, Thailand

Eulogy to Richard H Ward
XIX International Congress of Genetics, Melbourne

Complexity and Diversity and the Shape of 21^st Century Biotech/Pharma
Discovery Science and Biotechnology Conference, Sydney

Human Genetics in the 21^st Century
Australian Institute of Sport, Genetics in Sport Workshop, Canberra

Health Outcomes from Molecular Biotechnolgy: How Important is Human Diversity
Australian Academy of Technological Sciences and Engineering, Australia Japan Symposium on Biomedical Sciences:
Frontier Discovery of Life Sciences towards Applied Product, Melbourne

Y Fang

A Mathematical Model for Protein Folding
ISMB 2003, Brisbane, QLD

A Mathematical Model of Protein Folding
BioinfoSummer, Canberra, ACT

Smallpox, Bioterrorism and Emerging Infections
University of Third Age (U3A), Hughes Community Centre, Canberra, ACT

Smallpox, Bioterrorism and Emerging Infections
PhD students, The Australian National University, Canberra, ACT

Smallpox, Bioterrorism and Emerging Infections
Federation of University Women, The Australian National University, Canberra, ACT

Smallpox, Bioterrorism and Emerging Infections
Valedictory Symposium for Professor Ed Westaway, Brisbane, QLD

A Life of Work in Science and Medicine
Symposium: Ageing Well: a Time to Reflect, The Australian National University, Canberra, ACT

A Life of Work in Science and Medicine
CRES 30th Birthday Symposium: The 'I' Word: Thirty Years of Interdisciplinary Environmental Research and Education,
The Australian National University, Canberra, ACT

Smallpox Biosecurity, Preventing the Unthinkable
Teleconference Address: Tribute to DA Henderson, Geneva, Switzerland

How Bob got to The Australian National University
Introductory address, 11th Frank and Bobbie Fenner Conference, Shine Dome, Academy of Science, Canberra, ACT

Frank Fenner, Interview at home
Radio interview, 'Big Ideas' Program, Peter Thompson, ABC Radio National

Frank Fenner, Interview at home
'Australian Firsts' program by George Negus ABC TV
Commentator: Professor Richard Smallwood

The Fenner Building
Naming of Building 42, The Faculty of Science and The ANU Medical School, The Australian National University, Canberra, ACT

Address to Convocation
Conferring of Degrees Ceremony, The Australian National University, Canberra, ACT

PS Foster

Immune regulation and asthma
American Academy of Asthma Allergy and Immunology, Denver, Colorado USA

Interaction between eosinophils and Th2 cells
International Meeting of the Eosinophil Society, Aspen, Colorado USA

C Garcia

Genomic analysis of protective vs pathogenic antibody production
AB cell Dialogue, Melbourne, VIC

O Autoimmunity, Where art thy Genes?
Garvan Institute, Sydney, NSW

The new genetics: Managing the options they offer
The 2nd Annual Canberra Weekend of ideas: Science and Ethics
Manning Clarke House, Canberra, ACT

Stem cell research and human cloning: the principles, controversies and ethical dilemmas
"Cherchez la femme" series, Manning Clarke House, Canberra, ACT

C Goodnow

Mechanisms of Immunologic Tolerance and its Breakdown
Utah, USA

Genome-wide mutagenesis to reveal immune regulators
2003 Miami Nature Biotechnology Winter Symposium, Miami, USA

Tolerogenic versus immunogenic signalling
International Symposium on Regulation of Immune Response in Health and Disease, Osaka, Japan

Genetic analysis of pathways mediating T cell tolerance or immunity
Thyme Oz IV Incorporating Diabetes Oz, Heron Island, QLD

Targetting immunosuppression by genetic analysis of immunogenic versus tolerogenic signalling
TSANZ Transplant Society of Australia and New Zealand Annual Meeting, Canberra, ACT

Genetic Analysis of lymphocyte sensitivity to antigen
AAI-NIAD Symposium, Denver, USA

Elucidating cellular and molecular pathways for animal health and production by genome-wide mutagenesis in mice
Horizins in Livestock Sciences (The Impact of the New Biology), Gold Coast, QLD

Elucidating cellular and molecular pathways for human health by genome-wide mutagenesis in mice
Institute for Molecular Bioscience Research Seminar Series, Brisbane, QLD

Molecular analysis of pathways in diabetes
JDRF/Medibank Private Diabetes One, Canberra, ACT

Molecular analysis of pathways in diabetes
Diabetes One Symposium and Expo, Sydney, NSW

1st Australian B Cell Dialogue, Melbourne, VIC

The Human Genome: Decoding the Body's Disease Fighting Manual
ANU Institute of Bioscience Public Lecture, National Museum of Australia, Canberra, ACT

Regulation of lymphocyte numbers and function: analysis by genome-wide mutagenesis in mice
The 5^th Peter MacCallum Cancer Institute Symposium, The Molecular and Cell Biology of Cancer, Melbourne, VIC

The Human Genome: Decoding the Body's Disease Fighting Manual
Chancellor's Dinner, Sydney, NSW

Caveats on models of signalling mechanisms for cell survival and death
American Society for Neurochemistry, Newport Beach, USA

Role of intracellular calcium stores and gap junctions in myogenic activity in cerebral arteries
2nd International Symposium on Smooth Muscle Rhythmicity, Singapore

The heparan sulphate degrading enzyme heparanase: molecular basis of function and targeting with
drug inhibitors to treat cancer and inflammatory disease
GADI Research Institute, University of Canberra, Canberra, ACT

Early growth response 1 regulates inducible heparanase expression in activated T cells
33^rd Annual Scientific Meeting, Australasian Society for Immunology, Perth, WA

G Huttley

Evolutionary theory predicts epistasis involving BRCA1 will contribute to breast cancer risk
University of Melbourne, Murdoch Institute, Walter and Eliza Hall Institute joint seminar series, Melbourne, VIC

Adaptive modification to BRCA1 is a common feature of placental mammal evolution
19th International Congress of Genetics, Melbourne, VIC

A Isaev

Homogeneity of tube hypersurfaces in complex space
Differential Geometry Seminar, University of Adelaide, Adelaide, SA

The first stage of vision: Transduction and adaptation in retinal photoreceptors
Federation Fellows’ Dinner, University House, Australian National University, Canberra, ACT

Secrets of the retinoid cycle revealed by electrophysiology and psychophysics
‘Retinoids’, Seventh Annual Vision Research Meeting, ARVO, Ft Lauderdale, Florida, USA

Dark adaptation: Threshold elevation, ERG recovery, and pigment regeneration Seminar
Centre for Vision Science, RSBS, Australian National University, Canberra, ACT

Human photoreceptor responses measured using the electroretinogram Seminar
Anderson Stuart Series, University of Sydney, Sydney, NSW

The shut-off of the rod’s response to a single photon: Can ratcheting-down of R* activity by phosphorylation
account for the observed response variability?
Kenneth Craik Club, Cambridge, UK

Human photoreceptor responses measured from the ERG
Australasian Ophthalmic and Visual Sciences Meeting, Melbourne, VIC

International Workshop on Direction Selectivity in the Retina
Gatsby Computational Neuroscience Unit, University College, London, UK

J Maindonald

Predictive validation issues in data mining
First Queensland Statistics Conference, Toowoomba, QLD

Predictive Accuracy in Model Assessment
Department of Statistics, University of Western Ontario, London, Ontario, Canada

Using R for Fun and Professional Profit
Department of Epidemiology & Public Health, Imperial College, London, UK

The Role of Models in Predictive Validation (Statistics for Budding Data Miners)
ISI Meeting, Berlin, Germany

Predictive Accuracy in Model Assessment
Department of Mathematical Statistics, Lund Institute of Technology, Lund, Sweden

KI Matthaei

Human Cloning
Canberra Medico-Legal Society, Commonwealth Club, Canberra, ACT

How to make a knockout mouse and then keep it
Kioloa Neuroscience Meeting, Kioloa, NSW

Human therapeutic cloning
Combined Yass and Ginninderra Rotary Clubs, Murumbateman, NSW

Animal Models of Disease
Asthma & Allergy Institute, Perth, WA

Human cloning
Australian Academy of Science Lectures for Senior Citizens, Canberra, ACT

Are we getting the right answers from Gene Targeted and Transgenic Mice?
School of Biosciences, Cardiff University, Cardiff, Wales, UK

Human Cloning
Sunday Night Crews, Radio 2GB Sydney, NSW

Gene knockout mice: The answer or a problem?
Australian and New Zealand Microcirculation Society, 11th An nual Meeting, Kingfisher Resort, Fraser Island, QLD

Knockout mice: The answer or a problem?
Department of Biological Sciences, University of Wollongong, Wollongong, NSW

Knockout and Transgenic mice in Immunology
Division of Biochemistry and Molecular Biology, Faculty of Science, Australian National University, Canberra

Knockout mice: The answer or a problem?
Hanson Centre for Cancer Research IMVS, Adelaide, SA

Human Therapeutic Cloning, The New Genetics
Australian and New Zealand Medical Boards and Councils’ Annual Seminar, National Convention Centre, Canberra, ACT

S Oleskevich

Synaptic transmission in the auditory brainstem of deaf mice
Garvan Institute of Medical Research, Sydney, NSW

Heparan sulfate mimetics as inhibitors of cell migration, proliferation and invasion
Victor Chang Cardiac Research Institute, Sydney, NSW

New approaches to cancer immunotherapy
Brisbane Immunology Group, Caloundra, QLD

Heparan sulfate mimetics as inhibitors of vascular smooth muscle proliferation and intimal thickening
after balloon injury
ISA Satellite Symposium, Vascular Remodelling in Atherosclerosis and Restenosis, Kobe, Japan

Cancer immunotherapy by tumour-specific Th2 cells
The 5^th Peter MacCallum Cancer Institute Symposium, The Molecular and Cell Biology of Cancer, Melbourne, VIC

From bench to bedside: The trials and tribulations in the development of a new anti-cancer drug
The 5th Peter MacCallum Cancer Institute Symposium, The Molecular and Cell Biology of Cancer, Melbourne, VIC

Novel approaches to cancer immunotherapy
Commonwealth Serum Laboratories, Melbourne, VIC

Inhibition of inflammation by heparan sulfate mimetics
33rd Annual Scientific Meeting, Australasian Society for Immunology, Perth, WA

C Raymond

Calcium signals underlying the induction of different forms of LTP
Retirement Symposium for Prof Julian Jack, Oxford University, UK

Calcium signals underlying the induction of different forms of LTP
MRC Centre for Synaptic Plasticity, University of Bristol, UK

Calcium signals underlying the induction of different forms of LTP
Physiologisches Institut, University of Freiburg, Germany

Different calcium sources code for different forms of LTP
Australian Neuroscience Society Symposium: Calcium and Neuronal Function

Calcium buffering in nerve terminals
Retirement symposium for Julian Jack, Oxford University, UK

Transmission between spinal interneurons and motorneurons
Eccles Centenary Symposium, Canberra, ACT

Transient developmental appearance of myoendothelial gap junctions and
EDHF in rat saphenous artery
3rd Federation of European Physiological Societies, Nice, France

Essential Role of Myoendothelial Gap Junctions in EDH(F) Activity
Cardiovascular Centre and Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, USA

Endothelium-derived hyperpolarising factor and cell coupling: Factors and fiction?
Australian Physiological and Pharmacological Society, 70th Annual Meeting, University of Sydney, NSW

MF Shannon

c-Rel is required for chromatin remodelling across the interleukin-2 gene promoter
XIX International Congress of Genetics, Melbourne, VIC
c-Rel is required for chromatin remodelling across the interleukin-2 gene promoter
International Cytokine Society, Annual Meeting, Dublin, Ireland

c-Rel is required for chromatin remodelling across the interleukin-2 gene promoter
International Society for Interleron and Cytokine Research, Cairns, QLD

Chromatin remodelling and inducible gene transcription: lessons from the GM-CSF and IL-2 genes
Boston University School of Medicine, Boston, USA
Chromatin remodelling and inducible gene transcription: lessons from the GM-CSF and IL-2 genes
Centre for Blood Research, Harvard Medical School, Boston, USA

Chromatin remodelling on inducible genes in T cells
National Institutes of Health, Bethesda, MD, USA

Chromatin remodelling on inducible genes in T cells
Howard Hughes Medical Institute, UCLA, Los Angeles, USA

RM Slattery

Identification of a diabetes susceptibility gene
Monash/Baker AMREP, Melbourne, VIC

Role of MHC class I in TID
Diabetes Workshop

Initiation and propagation of action potentials in neurons of the central nervous system
Eccles Centenary Symposium, Canberra, ACT

Excitatory actions of GABA in the cortex
Max Planck Institute, Heidelberg, Germany

Excitatory actions of GABA in the cortex
Erasmus University, Rotterdam, Holland

Dendritic determinants of spike-timing dependent plasticity
University of Basel, Basel, Switzerland

Dendritic determinants of spike-timing dependent plasticity
University of Munich, Munich, Germany

Dendritic mechanisms involved in spike-timing dependent plasticity
University of Zurich, Zurich, Switzerland

A consensus sequence based scrambled antigen vaccine (SAVINE) incorporating all HIV-1 proteins
HIV Vaccine trials network full group meeting, Seattle, USA

Central auditory neurons and synapses in congenital peripheral deafness
Wright State University Neuroscience Symposium, 'Channels and Synapses - development of functional
properties of neuronal circuits', Dayton, Ohio, USA

Synaptic transmission in the cochlear nucleus
Eccles Centenary Symposium, Canberra, ACT

The new hypertension guidelines
WHO/ISH meeting on Pathophysiology and Prevention of Hypertension, Bagnaia, Italy

Statement on Management of Hypertension
WHO/ISH Global Consultative Workshop, Bangalore, India

Career management is for the birds
Australian Institute of Management Great Debate, Canberra, ACT

Strategic visioning for commercialisation — a researcher’s point of view
Knowledge Commercialisation Australia Conference, Canberra, ACT

Ernst and Young Women with Ambition breakfast speaker, Canberra, ACT

Hormones and the Heart
John Funder Festival Dinner, Melbourne, VIC

Medical Women’s Society of ACT, Canberra, ACT

Department of Finance, Women’s Network Conference, Canberra, ACT

Robert Vandongen Memorial Lecture, Royal Perth Hospital, Perth, WA

Women in Business, Women in Power, Canberra, ACT

S Wilson

Bioinformatics: An Overview
6th International Conference on Cellular Engineering, Sydney, NSW

Challenges in the Analysis of GeneChip Microarray data
BioInfoSummer, Canberra, ACT